Selective gonadotropin-releasing hormone (GnRH) receptor antagonist (Ki
values are 2.2, 3.8 and 6.0 nM for mouse, rat and human receptors respectively). Suppresses testosterone and luteinising hormone (LH) levels in vivo
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All Tocris products are intended for laboratory research use only.
Effect of testosterone suppression on the pharmacokinetics of a potent GnRH receptor antagonist.
Iatsimirskaia et al.
Biological characterization of a novel, orally active small molecule gonadotropin-releasing hormone (GnRH) antagonist using castrated and intact rats.
Anderes et al.