AG 205

Catalog # Availability Size / Price Qty
6242/25
6242/5
AG 205 | Additional Nuclear Receptor Compounds
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Description: Progesterone receptor membrane component 1 (Pgrmc1) ligand

Chemical Name: cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone

Purity: ≥98%

Product Details
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Biological Activity

AG 205 is a progesterone receptor membrane component 1 (Pgrmc1) ligand. Inhibits cell cycle progression and cell viability in cancer cell lines. Inhibits progesterone induced cytosolic Ca2+ increases in GnRH neurons in vitro.

Technical Data

M.Wt:
454.98
Formula:
C22H23ClN6OS
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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