Chemical Name: (2E)-3-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2-propenethioamide
Biological Activity Inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. Decreases cellular proliferation in human muscular sarcoma cell lines. Also inhibits ErbB2 and VEGFR-2 (IC50 values are approximately 1 μM for both).
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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