AG 879

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2617/10
AG 879 | CAS No. 148741-30-4 | Trk Receptor Inhibitors
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Description: TrkA inhibitor
Alternative Names: Tyrphostin AG 879

Chemical Name: (2E)-3-[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]-2-cyano-2-propenethioamide

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

Inhibitor of the tyrosine kinase activity of nerve growth factor (NGF) TrkA. Decreases cellular proliferation in human muscular sarcoma cell lines. Also inhibits ErbB2 and VEGFR-2 (IC50 values are approximately 1 μM for both).

Technical Data

M.Wt:
316.46
Formula:
C18H24N2OS
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
148741-30-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for AG 879

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