AGTR-1 Antibody Blocking Peptide

Novus Biologicals | Catalog # NB100-57073PEP

Novus Biologicals
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Key Product Details

Source

Synthetic

Applications

Antibody Competition
View all AGTR-1 Proteins and Enzymes »

Product Specifications

Description

A AGTR-1 antibody blocking peptide.

Source: Synthetic

Amino Acid Sequence: (Accession #: NP_0006761; NP_0048262; NP_0336111; NP_1140381; NP_1144381) C-EIQKNKPRNDDIFK

Purity

>50%, by HPLC

Application Notes

This peptide is useful as a blocking peptide for NB100-57073. For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NB100-57073PEP
Formulation Lyophilized from a 5 pmol/ul solution in 5% (v/v) acetonitrile/H2O and TFA salt.
Preservative No Preservative
Concentration Lyoph
Reconstitution Reconstitute in 200 ul distilled water to obtain a 0.5 mg/ml peptide solution.
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: AGTR-1

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least four transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants.

Long Name

Angiotensin II Receptor Type 1

Alternate Names

AG2S, AGTR1, AT1, AT1AR, AT1BR, AT1R, AT2R1

Gene Symbol

AGTR1

Additional AGTR-1 Products

Product Documents for AGTR-1 Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for AGTR-1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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FAQs

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Associated Pathways

Jak/STAT Signaling Pathway Jak/STAT Signaling Pathway Thumbnail