AH 6809

  ( 6 citations )    
Product Datasheet
Catalog Number:0671
Chemical Name:6-Isopropoxy-9-xanthone-2-carboxylic acid
Product Details
Citations (6)
Supplemental Products
Reviews
Biological Activity
Antagonist at prostaglandin EP1 (pA2 = 6.8) and EP2 (Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45).
Technical Data
  • M.Wt:
    298.3
  • Formula:
    C17H14O5
  • Solubility:
    Soluble to 100 mM in 1.1eq. NaOH and to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    33458-93-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for AH 6809 include:

6 Citations: Showing 1 - 6
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  1. Oxidized phospholipid OxPAPC activates TRPA1 and contributes to chronic inflammatory pain in mice
    Authors: Liu Et al.
    PLoS One  2016;11:e0165200
  2. Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization.
    Authors: Jansen Et al.
    Dent Res J (Isfahan)  2015;19:210
  3. Cholinergic Autoantibodies from Primary Sjögren's Syndrome Inhibit Mucin Production via Phospholipase C and Cyclooxygenase-2 In the Rat Submandibular Gland.
    Authors: Passafaro Et al.
    Br J Pharmacol  2011;8:138
  4. Protection of protease-activated receptor 2 mediated vasodilatation against angiotensin II-induced vascular dysfunction in mice.
    Authors: Chia Et al.
    BMC Pharmacol  2011;11:10
  5. Insulin induces airway smooth muscle contraction.
    Authors: Schaafsma Et al.
    J Pharmacol Exp Ther  2007;150:136
  6. Regulation of the human prostanoid TPalpha and TPbeta receptor isoforms mediated through activation of the EP(1) and IP receptors.
    Authors: Walsh and Kinsella
    Br J Pharmacol  2000;131:601

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