AH 6809

Key Product Details

Product Description

AH 6809 is an antagonist at prostaglandin EP₁ (pA₂ = 6.8) and EP₂ (K_i = 350 nM) receptors. Also weakly inhibits DP receptors (pA₂ = 4.45).

Product Specifications for AH 6809

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for AH 6809

The following data is based on the product molecular weight 298.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.35 mL	16.76 mL	33.52 mL
5 mM	0.67 mL	3.35 mL	6.70 mL
10 mM	0.34 mL	1.68 mL	3.35 mL
50 mM	0.07 mL	0.34 mL	0.67 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Coleman AH6809, a prostanoid EP₁-receptor blocking drug. Br.J.Pharmacol.
• Kiriyama Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. Br.J.Pharmacol. 1997 PMID: 9313928
• van der Merwe Prostaglandin E₂ derived from cyclooxygenases 1 and 2 mediates intestinal epithelial ion transport stimulated by the activation of protease-activated receptor 2. J.Pharmacol.Exp.Ther. 2009 PMID: 19190238
• Keery and Lumley AH 6809, a prostaglandin DP-receptor blocking drug on human platelets. Br.J.Pharmacol. 1988 PMID: 2460179

Product Documents for AH 6809