AH 6809

Catalog # Availability Size / Price Qty
AH 6809 | CAS No. 33458-93-4 | Prostanoid Receptor Antagonists
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Description: EP1 and EP2 receptor antagonist

Chemical Name: 6-Isopropoxy-9-xanthone-2-carboxylic acid

Purity: ≥98%

Product Details
Citations (6)
Supplemental Products

Biological Activity

AH 6809 is an antagonist at prostaglandin EP1 (pA2 = 6.8) and EP2 (Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45).

Technical Data

Soluble to 100 mM in 1.1eq. NaOH and to 100 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
    Kiriyama et al.
    Br.J.Pharmacol., 1997;122:217
  2. AH 6809, a prostaglandin DP-receptor blocking drug on human platelets.
    Keery and Lumley
    Br.J.Pharmacol., 1988;94:745
  3. Prostaglandin E2 derived from cyclooxygenases 1 and 2 mediates intestinal epithelial ion transport stimulated by the activation of protease-activated receptor 2.
    van der Merwe et al.
    J.Pharmacol.Exp.Ther., 2009;329:747
  4. AH6809, a prostanoid EP1-receptor blocking drug.
    Coleman et al.
    Br.J.Pharmacol., 1985;85:273P

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Citations for AH 6809

The citations listed below are publications that use Tocris products. Selected citations for AH 6809 include:

6 Citations: Showing 1 - 6


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