AH 6809

Catalog # Availability Size / Price Qty
0671/10
0671/50
AH 6809 | CAS No. 33458-93-4 | Prostanoid Receptor Antagonists
1 Image
Description: EP1 and EP2 receptor antagonist

Chemical Name: 6-Isopropoxy-9-xanthone-2-carboxylic acid

Purity: ≥98%

Product Details
Citations (6)
Supplemental Products
Reviews

Biological Activity

AH 6809 is an antagonist at prostaglandin EP1 (pA2 = 6.8) and EP2 (Ki = 350 nM) receptors. Also weakly inhibits DP receptors (pA2 = 4.45).

Technical Data

M.Wt:
298.3
Formula:
C17H14O5
Solubility:
Soluble to 100 mM in 1.1eq. NaOH and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
33458-93-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.
    Kiriyama et al.
    Br.J.Pharmacol., 1997;122:217
  2. AH 6809, a prostaglandin DP-receptor blocking drug on human platelets.
    Keery and Lumley
    Br.J.Pharmacol., 1988;94:745
  3. Prostaglandin E2 derived from cyclooxygenases 1 and 2 mediates intestinal epithelial ion transport stimulated by the activation of protease-activated receptor 2.
    van der Merwe et al.
    J.Pharmacol.Exp.Ther., 2009;329:747
  4. AH6809, a prostanoid EP1-receptor blocking drug.
    Coleman et al.
    Br.J.Pharmacol., 1985;85:273P

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citations for AH 6809

The citations listed below are publications that use Tocris products. Selected citations for AH 6809 include:

6 Citations: Showing 1 - 6

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for AH 6809

There are currently no reviews for this product. Be the first to review AH 6809 and earn rewards!

Have you used AH 6809?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.