AICDA Antibody Blocking Peptide

Novus Biologicals | Catalog # NBP1-77235PEP

Novus Biologicals
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Key Product Details

Source

Synthetic

Applications

Antibody Competition
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Product Specifications

Description

A blocking peptide containing 14 amino acids near the carboxy terminus of human AID.

Source: Synthetic

(Accession #: AAM95402)

Application Notes

This peptide is useful as a blocking peptide for NBP1-77235.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Scientific Data Images for AICDA Antibody Blocking Peptide

Western Blot: AICDA Antibody Blocking Peptide [NBP1-77235PEP]

Western Blot: AICDA Antibody Blocking Peptide [NBP1-77235PEP]

Western Blot: AICDA Peptide [NBP1-77235PEP] - blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37C

Formulation, Preparation, and Storage

NBP1-77235PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: AICDA

Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G.

Long Name

Activation-Induced Cytidine Deaminase

Alternate Names

AID, Arp2, CDA2, HIGM2

Gene Symbol

AICDA

Additional AICDA Products

Product Documents for AICDA Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for AICDA Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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