Recombinant Human AKR1A1 Protein

Novus Biologicals | Catalog # NBP1-30170

Novus Biologicals
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Key Product Details

Source

E. coli

Applications

SDS-PAGE
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Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids 1-325 of Human AKR1A1

Source: E.coli

Amino Acid Sequence: MAASCVLLHT GQKMPLIGLG TWKSEPGQVK AAVKYALSVG YRHIDCAAIY GNEPEIGEAL KEDVGPGKAV PREELFVTSK LWNTKHHPED VEPALRKTLA DLQLEYLDLY LMHWPYAFER GDNPFPKNAD GTICYDSTHY KETWKALEAL VAKGLVQALG LSNFNSRQID DILSVASVRP AVLQVECHPY LAQNELIAHC QARGLEVTAY SPLGSSDRAW RDPDEPVLLE EPVVLALAEKYGRSPAQILL RWQVQRKVIC IPKSITPSRI LQNIKVFDFT FSPEEMKQLN ALNKNWRYIV PMLTVDGKRV PRDAGHPLYP FNDPY

Purity

>90%, by SDS-PAGE

Predicted Molecular Mass

36.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human AKR1A1 Protein

Western Blot: Recombinant Human AKR1A1 Protein [NBP1-30170]

Western Blot: Recombinant Human AKR1A1 Protein [NBP1-30170]

Western Blot: AKR1A1 Protein [NBP1-30170] - AKR1A1 Protein 15% SDS-PAGE (3ug)

Formulation, Preparation, and Storage

NBP1-30170
Formulation 20 mM Tris-HCl buffer (pH8.0), 50 mM NaCl, 10% glycerol
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: AKR1A1

Alcohol dehydrogenase [NADP+] (AKR1A1) is a member of the aldo/keto reductase superfamily and catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. This protein is closely related (65% identity) to aldose reductase, an enzyme involved in the pathogenesis of some diabetic and galactosemic complications. It plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). Recombinant human Alcohol dehydrogenase was expressed in E.coli and purified by using conventional chromatography techniques.

Long Name

Aldo-keto reductase family 1 member A1

Alternate Names

Aldehyde reductase, ALDR1, EC 1.1.1.19, EC 1.1.1.2, EC 1.1.1.20, EC 1.1.1.372, EC 1.1.1.54

Gene Symbol

AKR1A1

Additional AKR1A1 Products

Product Documents for Recombinant Human AKR1A1 Protein

Certificate of Analysis

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Product Specific Notices for Recombinant Human AKR1A1 Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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