[Ala113]-MBP (104-118)
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Description: Protein kinase C inhibitor
Alternative Names: [Ala113]-Myelin Basic Protein (104-118)
Biological Activity
[Ala113]-MBP (104-118) is a synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).Technical Data
M.Wt:
1493.68
Formula:
C67H104N20O19
Sequence:
GKGRGLSLSAFSWGA
Solubility:
Soluble to 2 mg/ml in 0.25% acetic acid
Storage:
Desiccate at -20°C
CAS No:
99026-78-5
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Substrate specificity of phospholipid/Ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein.
Turner et al.
J.Biol.Chem., 1985;260:11503 -
Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C).
Su et al.
Biochem.Biophys.Res.Commun., 1986;134:78
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