Alprenolol hydrochloride
Tocris Bioscience | Catalog # 2806
Key Product Details
Description
Product Description
Alprenolol hydrochloride is a β-adrenoceptor (β2 > β1 > β3) and 5-HT1A receptor antagonist.
Product Specifications for Alprenolol hydrochloride
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 28.58 | 100 |
Preparing Stock Solutions for Alprenolol hydrochloride
The following data is based on the product molecular weight 285.81.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.50 mL | 17.49 mL | 34.99 mL |
| 5 mM | 0.70 mL | 3.50 mL | 7.00 mL |
| 10 mM | 0.35 mL | 1.75 mL | 3.50 mL |
| 50 mM | 0.07 mL | 0.35 mL | 0.70 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.
- Bjorvatin The 5-HT1A antagonist (-)-alprenolol fails to modify sleep or zimeldine-induced sleep-waking effects in rats. Pharmacol.Biochem.Behav. 1992 PMID: 1388278
- Baker The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors. Br.J.Pharmacol. 2005 PMID: 15655528
- Blue Antagonist characterization of atypical beta adrenoceptors in guinea pig ileum: blockade by alprenolol and dihydroalprenolol. J.Pharmacol.Exp.Ther. 1990 PMID: 1969469
Product Documents for Alprenolol hydrochloride
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Alprenolol hydrochloride
For research use only
Citations for Alprenolol hydrochloride
Customer Reviews for Alprenolol hydrochloride (1)
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Species: MouseAssay Type: Ex VivoCell Line/Tissue: Acute brain slicesVerified Customer | Posted 01/30/2018Beta-2 receptor blocker used in brain slices. No effect was found, although not sure if it was due to lack of blockade or lack of involvement of B2R in the observed process
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