Altanserin hydrochloride

Catalog # Availability Size / Price Qty
1809/10
1809/50
Altanserin hydrochloride | CAS No. 1135280-78-2 | 5-HT2A Receptor Antagonists
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Description: 5-HT2A receptor antagonist

Chemical Name: 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride

Purity: ≥98%

Product Details
Citations (2)
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Biological Activity

Potent and selective 5-HT2A receptor antagonist (Ki values are 0.13, 4.55, 40, 62 and 1570 nM at 5-HT2A, α1, 5-HT2C, D2 and 5-HT1A respectively). Centrally active following systemic administration in vivo.

Technical Data

M.Wt:
447.95
Formula:
C22H22FN3O2S.HCl
Solubility:
Soluble to 20 mM in DMSO with gentle warming
Purity:
≥98%
Storage:
Desiccate at +4°C
CAS No:
1135280-78-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Altanserin hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Altanserin hydrochloride include:

2 Citations: Showing 1 - 2

  1. Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network.
    Authors: Niebert Et al.
    Am J Physiol Regul Integr Comp Physiol  2011;6:e21395
  2. 5-HT2C-like receptors in the brain of Xenopus laevis initiate sex-typical fictive vocalizations.
    Authors: Yu and Yamaguchi
    J Neurophysiol  2009;102:752

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