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AM 114

  ( 1 citations )    
Product Datasheet
Catalog Number:2564
Chemical Name:3,5-Bis-[benzylidene-4-boronic acid]-1-methylpiperidin-4-one
Product Details
Citations (1)
Reviews
Biological Activity
Inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50 ~ 1 μM). Displays anticancer activity; inhibits cell growth in human colon cancer HCT116 p53+/+ cells (IC50 = 1.49 μM).
Technical Data
  • M.Wt:
    377.01
  • Formula:
    C20H21B2NO5
  • Solubility:
    Soluble to 10 mM in DMSO
  • Purity:
    >97
  • Storage:
    Store at +4°C
  • CAS No:
    856849-35-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Johns Hopkins University
Product Datasheets
SDS
COA view current batch
Citations:

The citations listed below are publications that use Tocris products. Selected citations for AM 114 include:

1 Citations: Showing 1 - 1

  1. Proteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cells.
    Authors: Dasgupta Et al.
    PLoS One  2014;9:e103604

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