AM 114

  ( 1 citations )    
Product Datasheet
Catalog Number:2564
Chemical Name:3,5-Bis-[benzylidene-4-boronic acid]-1-methylpiperidin-4-one
Product Details
Citations (1)
Reviews
Biological Activity
Inhibitor of the chymotrypsin-like activity of the 20S proteasome (IC50 ~ 1 μM). Displays anticancer activity; inhibits cell growth in human colon cancer HCT116 p53+/+ cells (IC50 = 1.49 μM).
Technical Data
  • M.Wt:
    377.01
  • Formula:
    C20H21B2NO5
  • Solubility:
    Soluble to 10 mM in DMSO
  • Purity:
    >97
  • Storage:
    Store at +4°C
  • CAS No:
    856849-35-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Johns Hopkins University
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for AM 114 include:

1 Citations: Showing 1 - 1

  1. Proteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cells.
    Authors: Dasgupta Et al.
    PLoS One  2014;9:e103604

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used AM 114?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee