Extremely potent, selective and rapidly reversible inhibitor of acetylcholinesterase (AChE) (IC50
values are 0.000698 and 8.20 μ
M at AChE and BChE respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Design, synthesis and biological evaluation of ambenonium derivatives as AChE inhibitors.
Bolognesi et al.
Ambenonium is a rapidly reversible noncovalent inhibitor of acetylcholinesterase, with one of the highest known affinities.
Hodge et al.
An investigation of the structure-activity correlations within a series of ambenonium analogs.
Lands et al.
Affinity for benzoquinonium, and ambenonium derivatives for the acetylcholine receptor, tested on the electroplax, and for acetylcholinesterase in solution.
The citations listed below are publications that use Tocris products. Selected citations for Ambenonium dichloride include:
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