AMBMP hydrochloride

Key Product Details

Product Description

AMBMP hydrochloride is a Wnt canonical signaling activator. Also inhibits tubulin polymerization. Suppresses TLR2/4/5-induced inflammatory response in human monocytes. Inhibits cell proliferation and induces cell cycle arrest in MDA-MB-231 breast cancer cells. Also decreases embryo to blastocyst development.

Product Specifications for AMBMP hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for AMBMP hydrochloride

The following data is based on the product molecular weight 386.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.59 mL	12.93 mL	25.85 mL
5 mM	0.52 mL	2.59 mL	5.17 mL
10 mM	0.26 mL	1.29 mL	2.59 mL
50 mM	0.05 mL	0.26 mL	0.52 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Denicol Canonical WNT signaling regulates development of bovine embryos to the blastocyst stage. Sci.Rep. 2013 PMID: 23405280
• Wang 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine is an anti-inflammatory TLR-2, -4 and -5 response mediator in human monocytes. Inflamm.Res. 2016 PMID: 26613980
• Fukuda Tubulin is a molecular target of the Wnt-activating chemical probe. BMC Biochem. 2016 PMID: 27207629
• Liu A small-molecule agonist of the Wnt signaling pathway. Angew.Chem.Int.Ed.Engl. 2005 PMID: 15724259

Product Documents for AMBMP hydrochloride