Ambrisentan

   
Product Datasheet
Catalog Number:5828
Chemical Name:(αS)-α-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid
Product Details
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Biological Activity
Selective endothelin receptor ETA antagonist. Displays approximately 200-fold selectivity for ETA over ETB (Ki values are 1 nM and 195 nM for respectively). Prevents endothelin-induced sudden death in rats.
Technical Data
  • M.Wt:
    378.42
  • Formula:
    C22H22N2O4
  • Solubility:
    Soluble to 38 mM in DMSO and to 38 mM in ethanol
  • Purity:
    >99
  • Storage:
    Store at +4°C
  • CAS No:
    177036-94-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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