Ambuic Acid

Tocris Bioscience | Catalog # 6547

Quorum sensing inhibitor; antibacterial
Tocris Bioscience
Discontinued Product
6547 has been discontinued. View all Antibiotics products.

Key Product Details

Description

Quorum sensing inhibitor; antibacterial
View all Antibiotics »

Product Description

Quorum sensing inhibitor. Inhibits auto-inducing peptide (AIP) signal biosynthesis in MRSA (IC50 = 2.5 μM). Reduces MRSA-induced abcess formation in rats. Exhibits activity against pathogenic Gram-positive bacteria but not commensal bacteria.

Product Specifications for Ambuic Acid

Molecular Weight

350.41

Formula

C19H26O6

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

(2E)-4-[(1R,5R,6R)-3-(1E)-1-Hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid

CAS Number

340774-69-8

PubChem ID

11152290

InChI Key

UDSQZJMGPSRCEM-HDKVZZTHSA-N

SMILES

CCCCC/C=C/C1=C([C@H]([C@H]2O[C@]2(C1=O)C/C=C(C(O)=O)\C)O)CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 1 3
Ethanol 1 3

Preparing Stock Solutions for Ambuic Acid

The following data is based on the product molecular weight 350.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.03 mM 95.13 mL 475.63 mL 951.27 mL
0.15 mM 19.03 mL 95.13 mL 190.25 mL
0.3 mM 9.51 mL 47.56 mL 95.13 mL
1.5 mM 1.90 mL 9.51 mL 19.03 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ambuic Acid

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ambuic Acid

For research use only

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