AMG 18 hydrochloride

Catalog # Availability Size / Price Qty
AMG 18 hydrochloride | CAS No. 2250019-92-0 | IRE1 Inhibitors
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Description: Potent and selective IRE1α inhibitor

Chemical Name: 2-Chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]benzenesulfonamide hydrochloride

Purity: ≥98%

Product Details
Citations (2)

Biological Activity

AMG 18 hydrochloride is a potent and selective IRE1α inhibitor (IC50 values are 13 and 99 nM for recombinant and cellular IRE1α, respectively). Exhibits selectivity for IRE1α in a panel of over 100 other kinases.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for AMG 18 hydrochloride

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