AMG 18 hydrochloride

Catalog # Availability Size / Price Qty
6166/5
Cat.No. 6166 - AMG 18 hydrochloride | C31H29ClN6O3S.HCl
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Description: Potent and selective IRE1α inhibitor

Chemical Name: 2-Chloro-N-[6-methyl-5-[[3-[2-[(3S)-3-piperidinylamino]-4-pyrimidinyl]-2-pyridinyl]oxy]-1-naphthalenyl]benzenesulfonamide hydrochloride

Purity: ≥98%

Product Details
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Biological Activity

Potent and selective IRE1α inhibitor (IC50 values are 13 and 99 nM for recombinant and cellular IRE1α, respectively). Exhibits selectivity for IRE1α in a panel of over 100 other kinases.

Technical Data

M.Wt:
637.58
Formula:
C31H29ClN6O3S.HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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