Aminopotentidine

Key Product Details

Product Description

Aminopotentidine is a H₂ antagonist (K_B values are 220 and 280 nM at human and guinea pig H₂ receptors respectively) and precursor for the synthesis of the [¹²⁵I]-iodo derivative.

Product Specifications for Aminopotentidine

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Aminopotentidine

The following data is based on the product molecular weight 477.60.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.09 mL	10.47 mL	20.94 mL
5 mM	0.42 mL	2.09 mL	4.19 mL
10 mM	0.21 mL	1.05 mL	2.09 mL
50 mM	0.04 mL	0.21 mL	0.42 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Ruat Reversible and irreversible labeling and autoradiographic localisation of the cerebral histamine H₂ receptor using [¹²⁵I]iodinated probes. Proc.Natl.Acad.Sci.USA 1990 PMID: 2308927
• Xie Synthesis and pharmacological characterization of novel fluorescent histamine H₂-receptor ligands derived from aminopotentidine. Bioorg.Med.Chem.Lett. 2006 PMID: 16730977
• Hirschfield Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H₂ receptor. J.Med.Chem. 1992 PMID: 1613748

Product Documents for Aminopotentidine