Chemical Name: Adenosine-5'-[(β,γ)-imido]triphosphate tetralithium salt
Biological ActivityAMP PNP is a non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
A novel brain ATPase with properties expected for the fast axonal transport motor.
Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage.
Yount et al.
KATP channels of mouse skeletal muscle: mechanism of channel blockage by AMP-PNP.
Hehl and Neumcke
Citations for AMP PNP
The citations listed below are publications that use Tocris products. Selected citations for AMP PNP include:
2 Citations: Showing 1 - 2
Conformational changes in the yeast mitochondrial ABC transporter Atm1 during the transport cycle.
Authors: Roland Et al.
Sci Adv 2021;7:eabk2392
Regulation of TRPV1 channel activities by intracellular ATP in the absence of capsaicin.
Authors: Shimizu Et al.
Biochim.Biophys.Acta Biomembr. 2021;1864:183782
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