Highly selective H2
agonist, slightly more potent than histamine itself. Only a weak antagonist at H3
and has no activity at H1
receptors. Induces vasodilation of cerebral arteries and decreases myogenic tone in vitro
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All Tocris products are intended for laboratory research use only.
Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazole.
Eriks et al.
Histamine decreases myogenic tone in rat cerebral arteries by H2-receptor-mediated Kv channel activation, independent of endothelium and cyclic AMP.
Jarajapu et al.
The new potent and selective histamine H2 receptor agonist amthamine as a tool to study gastric secretion.
Coruzzi et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1993;348:77
In vitro cardiac pharmacology of the new histamine H2 receptor agonist amthamine; comparisons with histamine and dimaprit.
Poli et al.
Agents Actions, 1993;40:44
The citations listed below are publications that use Tocris products. Selected citations for Amthamine dihydrobromide include:
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