Amthamine dihydrobromide

  ( 4 citations )    
Product Datasheet
Catalog Number:0668
Chemical Name:2-Amino-5-(2-aminoethyl)-4-methylthiazole dihydrobromide
Product Details
Citations (4)
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Reviews
Biological Activity
Highly selective H2 agonist, slightly more potent than histamine itself. Only a weak antagonist at H3 and has no activity at H1 receptors. Induces vasodilation of cerebral arteries and decreases myogenic tone in vitro.
Technical Data
  • M.Wt:
    319.06
  • Formula:
    C6H11N3S.2HBr
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >99
  • Storage:
    Desiccate at -20°C
  • CAS No:
    142457-00-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Amthamine dihydrobromide include:

4 Citations: Showing 1 - 4
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  1. Histamine H2 receptor signaling � environment interactions determine susceptibility to experimental allergic encephalomyelitis.
    Authors: Saligrama Et al.
    FASEB J  2014;28:1898
  2. Multidrug resistance protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation.
    Authors: Copsel Et al.
    J Biol Chem  2011;286:6979
  3. Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.
    Authors: Chigaev Et al.
    J Biol Chem  2011;286:20375
  4. Histamine-induced inhibition of leukotriene biosynthesis in human neutrophils: involvement of the H2 receptor and cAMP.
    Authors: Flamand Et al.
    Br J Pharmacol  2004;141:552

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