High affinity neuronal nicotinic ACh receptor partial agonist (Ki
values are 0.058, 0.26 and 7.2 μ
M for rat α
7, rat α
2 and fish skeletal muscle nAChRs respectively). Also stimulates Ca2+
-dependent catecholamine release from rat adrenomedullary cells in vitro
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Anabaseine is a potent agonist on muscle and neuronal alpha-bungarotoxin-sensitive nicotinic receptors.
Kem et al.
Neuronal nicotinic receptor β2 and β4 subunits confer large differences in agonist binding affinity.
Parker et al.
Desensitization of nicotinic agonist-induced [3H]γ-aminobutyric acid release from mouse brain synaptosomes is produced by subactivating concentrations of agonists.
Lu et al.
Effect of anabasine on catecholamine secreation from the perfused rat adrenal medulla.
Hong et al.