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Anastrozole

3388 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3388/10
3388/50

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Anastrozole | CAS No. 120511-73-1 | Cytochrome P450 Inhibitors
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Description: Potent aromatase (CYP19) inhibitor
Alternative Names: ZD1033

Chemical Name: α1,α1,α3,α3-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile

Purity: ≥99%

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Biological Activity

Anastrozole is a potent and highly selective aromatase (CYP19) inhibitor (IC50 = 15 nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo. Orally active.

Technical Data

M.Wt:
293.37
Formula:
C17H19N5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
120511-73-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes only under agreement from AstraZeneca

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