Aniracetam
Chemical Name: 1-(4-Methoxybenzoyl)-2-pyrrolidinone
Purity: ≥99%
Biological Activity
Aniracetam is a nootropic, with modulatory actions through allosteric potentiation of AMPA specific receptors, reduction of glutamate receptor desensitization and potentiation of metabotropic glutamate receptor activity. Anxiolytic following systemic administration.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Aniracetam reduces glutamate receptor desensitisation and slows the decay of fast excitatory synaptic currents in the hippocampus.
Isaacson and Nicholl
Proc.Natl.Acad.Sci.U.S.A., 1991;88:10936 -
Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam.
Ito et al.
J.Physiol., 1990;424:553 -
Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism.
Nakamura and Kurasawa
Eur.J.Pharmacol., 2001;420:33
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Citation for Aniracetam
The citations listed below are publications that use Tocris products. Selected citations for Aniracetam include:
1 Citation: Showing 1 - 1
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Retinohypothalamic tract synapses in the rat suprachiasmatic nucleus demonstrate short-term synaptic plasticity.
Authors: Moldavan and Allen
J Neurophysiol 2010;103:2390
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