Catalog Number: 0867
Chemical Name: 1-(4-Methoxybenzoyl)-2-pyrrolidinone
Biological Activity
Nootropic, with modulatory actions through allosteric potentiation of AMPA specific receptors, reduction of glutamate receptor desensitization and potentiation of metabotropic glutamate receptor activity. Anxiolytic following systemic administration.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 25 mM in ethanol and to 100 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Aniracetam reduces glutamate receptor desensitisation and slows the decay of fast excitatory synaptic currents in the hippocampus.
    Isaacson and Nicholl
    Proc.Natl.Acad.Sci.U.S.A., 1991;88:10936
  2. Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam.
    Ito et al.
    J.Physiol., 1990;424:553
  3. Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism.
    Nakamura and Kurasawa
    Eur.J.Pharmacol., 2001;420:33
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