Anthrax PA Antibody Blocking Peptide

Novus Biologicals | Catalog # NB100-55743PEP

Novus Biologicals
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Key Product Details

Applications

Antibody Competition
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Product Specifications

Application Notes

This peptide is useful as a blocking peptide for NB100-55743. For further blocking peptide related protocol, click here.

Specificity

This peptide is specific for NB100-55743 only.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NB100-55743PEP
Formulation Peptide dissolved in dH20. Contains no BSA.
Preservative No Preservative
Concentration 1 mg/ml
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -80C. Avoid freeze-thaw cycles.

Background: Anthrax PA

Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxic entry into cells. PA is secreted from Bacillus anthracis as an 83 kDa (PA83) protein which is cleaved by furin protease, releasing a 20 kDa fragment. The 63 kDa portion (PA63) of the cleavage product forms a heptamer, which binds the toxins LF and EF. This complex enters via receptor-mediated endocytosis where LF and EF exert their toxic effects.

Alternate Names

anthrax PA, Anthrax toxins translocating protein, Bacillus anthracis protective antigen, PA, PA 83, PA83, PAG, Paga, Protective antigen

Additional Anthrax PA Products

Product Documents for Anthrax PA Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for Anthrax PA Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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