Aphidicolin

Catalog # Availability Size / Price Qty
5736/1

Save Up to 40% on RUO Reagents with BIOSPRING24 (See Details)

Aphidicolin | CAS No. 38966-21-1 | RNA/DNA Polymerase Inhibitors
1 Image
Description: DNA polymerase α, δ and ε inhibitor

Chemical Name: (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Aphidicolin is a DNA polymerase α, δ and ε inhibitor. Exhibits selectivity over DNA polymerase β and γ. Antimitotic, antibiotic and antiviral.

Technical Data

M.Wt:
338.48
Formula:
C20H34O4
Solubility:
Soluble to 25 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
38966-21-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Control of DNA replication and cell proliferation in eukaryotes by aphidicolin.
    Spadari et al.
    Toxicol.Pathol., 1984;12:143
  2. Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium aphidicola.
    Bucknall et al.
    Antimicrob.Agents Chemother., 1973;4:294
  3. DNA polymerases α, δ, and ε: three distinct enzymes from HeLa cells.
    Syväoja et al.
    Proc.Natl.Acad.Sci.U.S.A., 1990;87:6664

Product Datasheets

Or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Aphidicolin

The citations listed below are publications that use Tocris products. Selected citations for Aphidicolin include:

1 Citation: Showing 1 - 1

  1. Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development.
    Authors: Clifford J Et al.
    Cell  2019;179:90-105.e21

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Aphidicolin

There are currently no reviews for this product. Be the first to review Aphidicolin and earn rewards!

Have you used Aphidicolin?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.