Aphidicolin

Key Product Details

Product Description

Aphidicolin is a DNA polymerase α, δ and ε inhibitor. Exhibits selectivity over DNA polymerase β and γ. Antimitotic, antibiotic and antiviral.

Product Specifications for Aphidicolin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Aphidicolin

The following data is based on the product molecular weight 338.48.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

8 7 6 5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.25 mM	11.82 mL	59.09 mL	118.18 mL
1.25 mM	2.36 mL	11.82 mL	23.64 mL
2.5 mM	1.18 mL	5.91 mL	11.82 mL
12.5 mM	0.24 mL	1.18 mL	2.36 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 24 publications citing the usage of this product.

• Bucknall Antiviral effects of aphidicolin, a new antibiotic produced by Cephalosporium aphidicola. Antimicrob.Agents Chemother. 1973 PMID: 4357181
• Syväoja DNA polymerases α, δ, and ε: three distinct enzymes from HeLa cells. Proc.Natl.Acad.Sci.U.S.A. 1990 PMID: 1975694
• Spadari Control of DNA replication and cell proliferation in eukaryotes by aphidicolin. Toxicol.Pathol. 1984 PMID: 11478315

Product Documents for Aphidicolin