Competitive serine protease inhibitor. Reversibly binds to and blocks the enzymatic active site. Inhibits a range of serine proteases including trypsin, chymotrypsin, kallikrein and plasmin.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
Elastase and tryptase govern TNFa-mediated production of active chemerin by adipocytes.
Parlee et al.
PLoS ONE, 2012;7:e51072
Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature.
Reichel et al.
PLoS ONE, 2011;6:e17229