APY 29

Catalog # Availability Size / Price Qty
4865/10
4865/50
Cat.No. 4865 - APY 29 | C17H16N8 | CAS No. 1216665-49-4
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Description: Inhibits IRE1α autophosphorylation; activates IRE1α endoribonuclease activity

Chemical Name: N2-1H-Benzimidazol-6-yl-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine

Purity: ≥98%

Product Details
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Biological Activity

Allosteric modulator of IRE1α. Inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α ribonuclease activity.

Technical Data

M.Wt:
332.36
Formula:
C17H16N8
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1216665-49-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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