AR-C 102222

Catalog # Availability Size / Price Qty
3969/10
3969/50
AR-C 102222 | CAS No. 1781934-50-6 | iNOS Inhibitors
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Description: Selective iNOS inhibitor

Chemical Name: 5-[(4'-Amino-5',8'-difluorospiro[piperidine-4,2'(1'H)-quinaxolin]-1-yl)carbonyl]-2-pyridinecarbonitrile hydrochloride

Purity: ≥98%

Product Details
Reviews

Biological Activity

Inducible nitric oxide synthase (iNOS) inhibitor; selective for iNOS over eNOS (IC50 values are 0.037 and >100 μM for iNOS and eNOS respectively). Exhibits antinociceptive and anti-inflammatory activity in rodent pain models.

Technical Data

M.Wt:
418.83
Formula:
C19H16F2N6O.HCl
Solubility:
Soluble to 25 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1781934-50-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of AstraZeneca UK Ltd.

Product Datasheets

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