Arbidol

Tocris Bioscience | Catalog # 7235

Inhibits replication of SARS-CoV-2 in vitro; broad spectrum antiviral
Tocris Bioscience
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Key Product Details

Description

Inhibits replication of SARS-CoV-2 in vitro; broad spectrum antiviral

Product Description

Arbidol is a broad spectrum antiviral. Displays activity against a range of respiratory and hepatitis viruses including influenza A, B and C, adenovirus, and hepatitis B and C. Increases stability of influenza viral hemagglutinins (HA) and prevents low-pH HA transition so inhibiting viral fusion. Also inhibits SARS-CoV-2 infection in vitro (IC50 = 4.11 μM).

Product Specifications for Arbidol

Molecular Weight

513.88

Formula

C22H25BrN2O3S.HCl

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

Ethyl 6-Bromo-4-((dimethylamino)methyl)-5-hydroxy-1-methyl-2-((phenylthio)methyl)-1H-indole-3-carboxylate hydrochloride

CAS Number

131707-23-8

PubChem ID

9958103

InChI Key

OMZHXQXQJGCSKN-UHFFFAOYSA-N

SMILES

Cl.CCOC(=O)C1=C(CSC2=CC=CC=C2)N(C)C2=CC(Br)=C(O)C(CN(C)C)=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 51.39 100
Ethanol 51.39 100

Preparing Stock Solutions for Arbidol

The following data is based on the product molecular weight 513.88.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.95 mL 9.73 mL 19.46 mL
5 mM 0.39 mL 1.95 mL 3.89 mL
10 mM 0.19 mL 0.97 mL 1.95 mL
50 mM 0.04 mL 0.19 mL 0.39 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Arbidol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Arbidol

For research use only

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