ARC 239 dihydrochloride

Tocris Bioscience | Catalog # 0928

α2B antagonist
Tocris Bioscience

Key Product Details

Description

α2B antagonist
View all Adrenergic alpha-2 Receptor Antagonists »

Product Description

ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively).

Licensing Information

Sold with the permission of Boehringer Ingelheim GmbH

Product Specifications for ARC 239 dihydrochloride

Molecular Weight

480.43

Formula

C24H29N3O3.2HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

2-[2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride

CAS Number

55974-42-0

PubChem ID

10345075

InChI Key

SAJKHRHHDGSJEZ-UHFFFAOYSA-N

SMILES

Cl.Cl.COC1=CC=CC=C1N1CCN(CCN2C(=O)C3=C(C=CC=C3)C(C)(C)C2=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 48.04 100

Preparing Stock Solutions for ARC 239 dihydrochloride

The following data is based on the product molecular weight 480.43.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.08 mL 10.41 mL 20.81 mL
5 mM 0.42 mL 2.08 mL 4.16 mL
10 mM 0.21 mL 1.04 mL 2.08 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for ARC 239 dihydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ARC 239 dihydrochloride

For research use only

Citations for ARC 239 dihydrochloride

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