adrenoceptor antagonist (pKD
values are 8.8, 6.7 and 6.4 at α2B
, and α2D
receptors respectively). Also available as part of the α2-Adrenoceptor Tocriset™
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Sold with the permission of Boehringer Ingelheim GmbH
Alpha-2A and alpha-2B adrenergic subtypes: antagonist binding in tissues and cell lines containing only one subtype.
Bylund et al.
Characterisation of sensory neurotransmission and its inhibition via α2B-adrenoceptors and via non-α2 adrenoceptors in rabbit iris.
Fuder and Selback
Naunyn Schmiedebergs Arch.Pharmacol., 1993;347:394