Biological Activity[Arg8]-Vasopressin is an antidiuretic hormone found in most mammalian species. Also acts as a neurotransmitter at synapses in the brain; increases [Ca2+]i in cultured rat hippocampal neurons.
(Modifications: Disulfide bridge between 1 - 6, Gly-9 = C-terminal amide)
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[Arg8]-vasopressin-induced increase in intracellular Ca2+ concentration in cultutred rat hippocampal neurons.
Migara et al.
Brain Res.Bull., 1999;49:343
Control of renal medulaary circulation by vasopressin V1 and V2 receptors in the rat.
Cowley et al.
Discovery and design of novel and selective vasopressin and oxyt. agonists and antagonists: the role of bioassays.
Chan et al.
Citations for [Arg8]-Vasopressin
The citations listed below are publications that use Tocris products. Selected citations for [Arg8]-Vasopressin include:
2 Citations: Showing 1 - 2
A circuit from hippocampal CA2 to lateral septum disinhibits social aggression.
Authors: Leroy Et al.
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW.
Authors: Nøhr Et al.
Neurochem Int 2017;102:105
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To determine the signaling pathways mediating the effect of V1 vasopressin VP, cells were incubated in the presence and absence of inhibitors.The role of protein kinases C (PKC) and B (PKB) mediating VP induced antiapoptosis in H32 cells was investigated.