ARP 101

Key Product Details

Product Description

ARP 101 is a selective inhibitor of MMP-2 that displays ~ 600-fold selectivity over MMP-1 (IC₅₀ values are 0.81 and 486 nM respectively).

Product Specifications for ARP 101

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for ARP 101

The following data is based on the product molecular weight 406.50.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.46 mL	12.30 mL	24.60 mL
5 mM	0.49 mL	2.46 mL	4.92 mL
10 mM	0.25 mL	1.23 mL	2.46 mL
50 mM	0.05 mL	0.25 mL	0.49 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 20 publications citing the usage of this product.

• Tuccinardi Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3 methylbutanamides. Bioorg.Med.Chem. 2006 PMID: 16483784

Product Documents for ARP 101