Catalog Number: 2446
Chemical Name: Ammonium trichloro[1,2-ethanediolato-O,O']-tellurate
Biological Activity
Immunomodulator; inhibits IL-10 synthesis and potentiates IL-1α, IL-2 and TNF-α release.
Technical Data
  • M.Wt:
    312.05
  • Formula:
    C2H4Cl3O2Te.NH4
  • Solubility:
    Soluble to 5 mM in DMSO with gentle warming and to 5 mM in ethanol with gentle warming
  • Storage:
    Desiccate at RT
  • CAS No:
    106566-58-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of interleukin-10 by the immunomodulator AS101 reduces mesangial cell proliferation in experimental mesangioproliferative glomerulonephritis.
    Kalechman et al.
    J.Biol.Chem., 2004;279:24724
Citations:

The citations listed below are publications that use Tocris products. Selected citations for AS 101 include:

1 Citations: Showing 1 - 1

  1. NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis.
    Authors: Souza-Fonseca-Guimaraes Et al.
    J Immunol 2012;188:5850

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