ATI 2341

Catalog # Availability Size / Price Qty
5795/1
ATI 2341
1 Image
Description: CXCR4 allosteric agonist
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Biological Activity

CXCR4 allosteric agonist (EC50 = 194 nM). Induces chemotaxis in CXCR4-expressing cells in vitro. Mobilizes polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) from bone marrow niche in vivo. Exhibits biased signaling towards Gi proteins over G13 and β-arrestin.

Technical Data

M.Wt:
2256.82
Formula:
C104H178N26O25S2
Sequence:
MGYQKKLRSMTDKYRL

(Modifications: Met-1 = N-terminal Palmitoyl)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
1337878-62-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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