Biological Activity CXCR4 allosteric agonist (EC 50 = 194 nM). Induces chemotaxis in CXCR4-expressing cells in vitro. Mobilizes polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) from bone marrow niche in vivo. Exhibits biased signaling towards G i proteins over G 13 and β-arrestin.
(Modifications: Met-1 = N-terminal Palmitoyl)
Soluble to 1 mg/ml in water
Store at -20°C
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