Attractin Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-87967

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all Attractin Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LLLSDILVFTSEQCDAHRSEAACLAAGPGIRCVWNTGSSQCISWALATDEQEEKLKSECFSKRTLDHDRCDQHTDCYSCTANTNDCHWCNDHCVPRNHSCSEGQISIFRYENCPKDNPMYYCNKKTSCRSCALDQNCQWE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (89%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

159 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Attractin Antibody - BSA Free

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967]

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967]

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967] - Staining of human small intestine shows weak cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967]

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967]

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967] - Staining of human cervix, uterine shows weak membranous positivity in squamous epithelial cells.
Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967]

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967]

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967] - Staining of human liver shows very weak membranous positivity in hepatocytes.
Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967]

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967]

Immunohistochemistry-Paraffin: Attractin Antibody [NBP1-87967] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

Applications for Attractin Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200-1:500
Application Notes
IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Attractin

Attractin is a serum glycoprotein of 175 kDaand found in both membrane-bound and secreted forms as a result of alternative splicing. Both the secreted and membrane-bound forms of attractin may be involved in the development and maintenance of the central nervous system. Membrane-bound attractin is a co-receptor for Agouti, antagonist of melanocortin-1 receptor. Secreted attractin, expressed by activated T lymphocytes and modulates interactions between T cells and monocytes/macrophages, was examined as a potential marker of immune activity. Attractinmay be a component of a pathway for regulated protein turnover that also involves mahogunin, a wide-expressed E3 ubiquitinligase found at particularly high levels in the brain. Attractinwas considered as an extracellular target amenable for the development of obesity-regulating drugs, also.

Alternate Names

ATRN, DPPT-L, Mahogany Protein, MGCA

Entrez Gene IDs

8455 (Human)

Gene Symbol

ATRN

UniProt

O75882

Additional Attractin Products

Product Documents for Attractin Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for Attractin Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for Attractin Antibody - BSA Free

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Protocols

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