Chemical Name: 1H-Indole-3-acetic acid
Biological ActivityChemical dimerizer used in auxin-inducible degron (AID) systems. Induces degradation of a target protein tagged with the auxin-receptor F-box protein Tir1 E3 ligase AID in human colorectral cancer and mouse ES cells or tagged with AFB2 in A431 cells. Endogenous plant hormone.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
An auxin-based degron system for the rapid depletion of proteins in nonplant cells.
Nishimura et al.
Rapid protein depletion in human cells by auxin-inducible degron tagging with short homology donors.
Natsume et al.
Cell Rep., 2016;15:210
An efficient auxin-inducible degron system with low basal degradation in human cells.
Li et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Auxin
There are currently no reviews for this product. Be the first to review Auxin and earn rewards!
Have you used Auxin?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image