Avasimibe

Catalog # Availability Size / Price Qty
6505/25
6505/5
Cat.No. 6505 - Avasimibe | C29H43NO4S | CAS No. 166518-60-1
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Description: ACAT inhibitor

Chemical Name: 2,6-Diisopropylphenyl (2-(2,4,6-triisopropylphenyl)acetyl)sulfamate

Purity: ≥98%

Product Details
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Biological Activity

ACAT inhibitor (IC50 = 3.3 μM). Inhibits cholesterol esterification and reduces plasma cholesterol levels in rats. Also inhibits tumor growth and prolongs survival time in a melanoma mouse model and reduces tumor growth and metastasis in a pancreatic cancer mouse model.

Technical Data

M.Wt:
501.72
Formula:
C29H43NO4S
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
166518-60-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold for research purposes under agreement from Pfizer Inc.

Product Datasheets

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