AZ PFKFB3 67
Chemical Name: (2S)-N-[4-[[3-Cyano-1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-indol-5-yl]oxy]phenyl]-2-pyrrolidinecarboxamide
Biological ActivityAZ PFKFB3 67 is a potent and selective PFKFB3 inhibitor (IC50 values are 11, 159 and 1130 nM for PFKFB3, PFKFB2 and PFKFB1 respectively).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Structure-based design of potent and selective inhibitors of the metabolic kinase PFKFB3.
Boyd et al.
Citation for AZ PFKFB3 67
The citations listed below are publications that use Tocris products. Selected citations for AZ PFKFB3 67 include:
1 Citation: Showing 1 - 1
LncRNA wires up Hippo and Hedgehog signaling to reprogramme glucose metabolism.
Authors: Zheng Et al.
EMBO J 2017;36:3325
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