BACE-2 Antibody Blocking Peptide

Novus Biologicals | Catalog # NBP1-77308PEP

Novus Biologicals
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Key Product Details

Source

Synthetic

Applications

Antibody Competition
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Product Specifications

Description

A blocking peptide containing 16 amino acids near the carboxy terminus of human BACE2.

Source: Synthetic

(Accession #: AAF17078)

Application Notes

This peptide is useful as a blocking peptide for NBP1-77308.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Scientific Data Images for BACE-2 Antibody Blocking Peptide

Western Blot: BACE-2 Antibody Blocking Peptide [NBP1-77308PEP]

Western Blot: BACE-2 Antibody Blocking Peptide [NBP1-77308PEP]

Western Blot: BACE2 Peptide [NBP1-77308PEP] - blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37C

Formulation, Preparation, and Storage

NBP1-77308PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: BACE-2

BACE2 (Memapsin 1) is a membrane-bound aspartic protease that is highly homologous with BACE1 (Memapsin 2). While BACE1 processes the amyloid precursor protein (APP) at a key step in generating the beta-amyloid peptide and presumably causes Alzheimer's disease (AD), BACE2 has not been demonstrated to be directly involved in APP processing, and its physiological functions remain to be determined. In vivo, BACE2 is expressed as a precursor protein containing pre-, pro-, protease, transmembrane, and cytosolic domains/peptides.

Long Name

beta-site Ayloid Precursor Protein Cleaving Enzyme 2

Alternate Names

BACE2

Gene Symbol

BACE2

Additional BACE-2 Products

Product Documents for BACE-2 Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for BACE-2 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Related Research Areas

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