BAPTA

Catalog # Availability Size / Price Qty
2786/100
BAPTA | CAS No. 85233-19-8 | Buffers, Chelators and Reagents
1 Image
Description: Selective calcium chelator

Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid

Purity: ≥95%

Product Details
Citations (17)
Reviews (1)

Biological Activity

Selective calcium chelator.

Technical Data

M.Wt:
476.23
Formula:
C22H24N2O10
Solubility:
Soluble to 50 mM in sodium bicarbonate (0.3N)
Purity:
≥95%
Storage:
Store at +4°C
CAS No:
85233-19-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for BAPTA

The citations listed below are publications that use Tocris products. Selected citations for BAPTA include:

17 Citations: Showing 1 - 10

  1. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.
    Authors: Chefetz Et al.
    Cell Rep  2019;26:3061
  2. Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory.
    Authors: Leroy Et al.
    Neuron  2017;95:1089
  3. Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma.
    Authors: Florea Et al.
    Oncotarget  2017;8:22876
  4. mGluR long-term depression regulates GluA2 association with COPII vesicles and exit from the endoplasmic reticulum.
    Authors: Pick Et al.
    EMBO J  2017;36:232
  5. Presynaptic Spike Timing-Dependent Long-Term Depression in the Mouse Hippocampus.
    Authors: Andrade-Talavera Et al.
    Cereb Cortex  2016;26:3637
  6. Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss.
    Authors: Birnbaum Et al.
    PLoS One  2015;6:e1791
  7. Sex Differences in Molecular Signaling at Inhibitory Synapses in the Hippocampus.
    Authors: Tabatadze Et al.
    J Neurosci  2015;35:11252
  8. NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking.
    Authors: Pleil Et al.
    Nat Neurosci  2015;18:545
  9. A critical role for the transient receptor potential channel type 6 in human platelet activation.
    Authors: Vemana Et al.
    Cell Commun Signal  2015;10:e0125764
  10. Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord.
    Authors: Carlsen and Perrier
    Front Neural Circuits  2014;8:60

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Study of remote regulation of calcium ions
By Lutpine Rachel on 01/02/2020
Application: Species: Human

In order to permit remote regulation of Ca2+, a selective BAPTA-type synthetic receptor / host was integrated with a photoswitchable azobenzene motif, which upon photoirradiation would enhance (or diminish) the capacity to bind calcium upon acting on the conformation of the adjacent binding site, rendering it a stronger or weaker binder.


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