Catalog Number: 2786
Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid
Biological Activity
Selective calcium chelator.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in sodium bicarbonate (0.3N)
  • Purity:
  • Storage:
    Store at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA.
    Cell Calcium, 2005;38:547

The citations listed below are publications that use Tocris products. Selected citations for BAPTA include:

Showing Results 1 - 10 of 10

  1. Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss.
    Authors: Birnbaum Et al.
    PLoS One
  2. Sex Differences in Molecular Signaling at Inhibitory Synapses in the Hippocampus.
    Authors: Tabatadze Et al.
    J Neurosci
  3. NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking.
    Authors: Pleil Et al.
    Nat Neurosci
  4. A critical role for the transient receptor potential channel type 6 in human platelet activation.
    Authors: Vemana Et al.
    Cell Commun Signal
  5. Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord.
    Authors: Carlsen and Perrier
    Front Neural Circuits
  6. Distinct molecular components for thalamic- and cortical-dependent plasticity in the lateral amygdala.
    Authors: Mirante Et al.
    Cell Death Dis
  7. Synaptic NMDA receptor-dependent Ca2+ entry drives membrane potential and Ca2+ oscillations in spinal ventral horn neurons.
    Authors: Alpert and Alford
    PLoS One
  8. Astrocytes mediate in vivo cholinergic-induced synaptic plasticity.
    Authors: Navarrete Et al.
    PLoS Biol
  9. Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A.
    Authors: Arozarena Et al.
    Cancer Cell
  10. Phorbol 12-myristate 13-acetate potentiation of N-methyl-D-aspartate-induced currents in primary cultured cerebellar granule cells is mediated by protein kinase C alpha.
    Authors: Reneau Et al.
    J Pharmacol Exp Ther
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

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