Catalog Number: 2786
Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid
Biological Activity
Selective calcium chelator.
Technical Data
  • M.Wt:
    476.23
  • Formula:
    C22H24N2O10
  • Solubility:
    Soluble to 50 mM in sodium bicarbonate (0.3N)
  • Purity:
    >95%
  • Storage:
    Store at +4°C
  • CAS No:
    85233-19-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA.
    Hardie
    Cell Calcium, 2005;38:547
Citations:

The citations listed below are publications that use Tocris products. Selected citations for BAPTA include:

10 Citations: Showing 1 - 10
Filter your results:

  1. Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss.
    Authors: Birnbaum Et al.
    PLoS One 2015;6:e1791
  2. Sex Differences in Molecular Signaling at Inhibitory Synapses in the Hippocampus.
    Authors: Tabatadze Et al.
    J Neurosci 2015;35:11252
  3. NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking.
    Authors: Pleil Et al.
    Nat Neurosci 2015;18:545
  4. A critical role for the transient receptor potential channel type 6 in human platelet activation.
    Authors: Vemana Et al.
    Cell Commun Signal 2015;10:e0125764
  5. Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord.
    Authors: Carlsen and Perrier
    Front Neural Circuits 2014;8:60
  6. Distinct molecular components for thalamic- and cortical-dependent plasticity in the lateral amygdala.
    Authors: Mirante Et al.
    Cell Death Dis 2014;7:62
  7. Synaptic NMDA receptor-dependent Ca2+ entry drives membrane potential and Ca2+ oscillations in spinal ventral horn neurons.
    Authors: Alpert and Alford
    PLoS One 2013;8:e63154
  8. Astrocytes mediate in vivo cholinergic-induced synaptic plasticity.
    Authors: Navarrete Et al.
    PLoS Biol 2012;10:e1001259
  9. Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A.
    Authors: Arozarena Et al.
    Cancer Cell 2011;19:45
  10. Phorbol 12-myristate 13-acetate potentiation of N-methyl-D-aspartate-induced currents in primary cultured cerebellar granule cells is mediated by protein kinase C alpha.
    Authors: Reneau Et al.
    J Pharmacol Exp Ther 2009;330:641

Have you used BAPTA?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information