Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid
Biological ActivitySelective calcium chelator.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Citations for BAPTA
The citations listed below are publications that use Tocris products. Selected citations for BAPTA include:
17 Citations: Showing 1 - 10
A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.
Authors: Chefetz Et al.
Cell Rep 2019;26:3061
Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory.
Authors: Leroy Et al.
Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma.
Authors: Florea Et al.
mGluR long-term depression regulates GluA2 association with COPII vesicles and exit from the endoplasmic reticulum.
Authors: Pick Et al.
EMBO J 2017;36:232
Presynaptic Spike Timing-Dependent Long-Term Depression in the Mouse Hippocampus.
Authors: Andrade-Talavera Et al.
Cereb Cortex 2016;26:3637
Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss.
Authors: Birnbaum Et al.
PLoS One 2015;6:e1791
Sex Differences in Molecular Signaling at Inhibitory Synapses in the Hippocampus.
Authors: Tabatadze Et al.
J Neurosci 2015;35:11252
NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking.
Authors: Pleil Et al.
Nat Neurosci 2015;18:545
A critical role for the transient receptor potential channel type 6 in human platelet activation.
Authors: Vemana Et al.
Cell Commun Signal 2015;10:e0125764
Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord.
Authors: Carlsen and Perrier
Front Neural Circuits 2014;8:60
Distinct molecular components for thalamic- and cortical-dependent plasticity in the lateral amygdala.
Authors: Mirante Et al.
Cell Death Dis 2014;7:62
DArgic modulation of GABAergic transmission in the entorhinal cortex: concerted roles of α1 adrenoreceptors, inward rectifier K+, and T-type Ca2+ channels.
Authors: Cilz Et al.
Cereb Cortex 2014;24:3195
Synaptic NMDA receptor-dependent Ca2+ entry drives membrane potential and Ca2+ oscillations in spinal ventral horn neurons.
Authors: Alpert and Alford
PLoS One 2013;8:e63154
Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP.
Authors: Kaeser-Woo Et al.
J Neurosci 2013;33:9769
Astrocytes mediate in vivo cholinergic-induced synaptic plasticity.
Authors: Navarrete Et al.
PLoS Biol 2012;10:e1001259
Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A.
Authors: Arozarena Et al.
Cancer Cell 2011;19:45
Phorbol 12-myristate 13-acetate potentiation of N-MthD.-aspartate-induced currents in primary cultured cerebellar granule cells is mediated by protein kinase C alpha.
Authors: Reneau Et al.
J Pharmacol Exp Ther 2009;330:641
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In order to permit remote regulation of Ca2+, a selective BAPTA-type synthetic receptor / host was integrated with a photoswitchable azobenzene motif, which upon photoirradiation would enhance (or diminish) the capacity to bind calcium upon acting on the conformation of the adjacent binding site, rendering it a stronger or weaker binder.