Cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. Designed based on the Bax-binding domain of human Ku70. Inhibits Bax-mediated apoptosis in vitro
. Shown to inhibit anti-cancer drug-induced apoptosis in vitro
. Negative control
(Cat. No. 1787) available.
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Other Product-Specific Information:
Bax-inhibiting peptide derived from mouse and rat Ku70.
Yoshida et al.
The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo.
Sawatzky et al.
The citations listed below are publications that use Tocris products. Selected citations for Bax inhibitor peptide V5 include:
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