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Bax inhibitor peptide V5

1785 2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1785/1
Bax inhibitor peptide V5
1 Image
Description: Inhibitor of Bax-mediated apoptosis
Product Details
Citations (2)
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

Cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. Designed based on the Bax-binding domain of human Ku70. Inhibits Bax-mediated apoptosis in vitro. Shown to inhibit anti-cancer drug-induced apoptosis in vitro.

Control Peptide also available.

Technical Data

M.Wt:
586.79
Formula:
C27H50N6O6S
Sequence:
VPMLK
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
579492-81-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license
Other Product-Specific Information:

Product Datasheets

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Reconstitution Calculator

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Citations for Bax inhibitor peptide V5

The citations listed below are publications that use Tocris products. Selected citations for Bax inhibitor peptide V5 include:

2 Citations: Showing 1 - 2

  1. Andrographolide sensitizes the cytotoxicity of human colorectal carcinoma cells toward cisp. via enhancing apoptosis pathways in vitro and in vivo.
    Authors: Lin Et al.
    Toxicol Sci  2014;139:108
  2. Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells.
    Authors: Lee Et al.
    J Cell Sci  2010;123:1634

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