Bax inhibitor peptide V5
Biological Activity
Cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. Designed based on the Bax-binding domain of human Ku70. Inhibits Bax-mediated apoptosis in vitro. Shown to inhibit anti-cancer drug-induced apoptosis in vitro.Control Peptide also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo.
Sawatzky et al.
Am.J.Pathol., 2006;168:33 -
Bax-inhibiting peptide derived from mouse and rat Ku70.
Yoshida et al.
Biochem.Biophys.Res.Commun., 2004;321:961
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citations for Bax inhibitor peptide V5
The citations listed below are publications that use Tocris products. Selected citations for Bax inhibitor peptide V5 include:
2 Citations: Showing 1 - 2
-
Andrographolide sensitizes the cytotoxicity of human colorectal carcinoma cells toward cisp. via enhancing apoptosis pathways in vitro and in vivo.
Authors: Lin Et al.
Toxicol Sci 2014;139:108
-
Angiotensin-II-induced apoptosis requires regulation of nucleolin and Bcl-xL by SHP-2 in primary lung endothelial cells.
Authors: Lee Et al.
J Cell Sci 2010;123:1634
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsReviews for Bax inhibitor peptide V5
There are currently no reviews for this product. Be the first to review Bax inhibitor peptide V5 and earn rewards!
Have you used Bax inhibitor peptide V5?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
