Biological Activity Guanylyl cyclase (sGC) stimulator. Increases activity of sGC by up to 92-fold at concentrations up to 100 μM. Induces relaxation of aorta, saphenous arteries, coronary arteries and veins in vitro. Inhibits collagen-induced platelet aggregation. Promotes lipid uptake into brown adipose tissue and increases energy expenditure in mice. Induces weight loss in obese mice. Antihypertensive.
Soluble to 10 mM in DMSO with gentle warming
Store at -20°C
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For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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