Chemical Name: (2S)-1-(3-Azabicyclo[3.1.0]hex-3-ylcarbonyl)-N-(2-cyclopropylethyl)-2,3,4,5-tetrahydro-2-methyl-4-oxo-1H-1,5-benzodiazepine-7-carboxamide
Biological ActivityPotent SMYD3 inhibitor (IC50 = 70 nM for inhibition of MEKK2 methylation in cells). Exhibits >100-fold selectivity for SMYD3 over other histone methyltransferases.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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