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BAY 9835

Catalog #: 8826 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8826/2

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BAY 9835 | CAS No. 3032487-31-0 | Synthetic Metalloprotease Inhibitors
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Description: Potent ADAMTS7 and ADAMTS12 inhibitor

Chemical Name: 5,6-Difluoro-N-[[(4S)-4-(1-methyl-1H-pyrazol-5-yl)-2,5-dioxo-4-imidazolidinyl]methyl]-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamide

Purity: ≥98%

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Biological Activity

BAY 9835 is a potent ADAMTS7 and ADAMTS12 inhibitor (IC50 values are 6 nM and 30 nM, respectively). BAY 9835 is selective over other metalloproteases (ADAMTS4, ADAMTS5, ADAM8, ADAM10, ADAM17, MMP2, MMP12, MMP14, MMP15). BAY 9835 is the first orally bioavailable ADAMTS7 inhibitor.

Technical Data

M.Wt:
493.39
Formula:
C22H16F5N5O3
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
3032487-31-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the BAY 9835 probe summary on the SGC website.

Product Datasheets

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