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BC 11-38

4496 1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4496/10
4496/50
BC 11-38 | CAS No. 686770-80-9 | Phosphodiesterase Inhibitors
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Description: Selective PDE11 inhibitor

Chemical Name: 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

BC 11-38 is a selective phosphodiesterase (PDE) 11 inhibitor (IC50 = 0.28 μM for PDE11; IC50 values are >100 μM for PDE1 - PDE10). Significantly elevates cAMP levels and cortisol production in H295R human adenocarcinoma cells.

Technical Data

M.Wt:
304.43
Formula:
C15H16N2OS2
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
686770-80-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for BC 11-38

The citations listed below are publications that use Tocris products. Selected citations for BC 11-38 include:

1 Citation: Showing 1 - 1

  1. p54nrb/NONO regulates cyclic AMP-dependent glucocorticoid production by modulating phosphodiesterase mRNA splicing and degradation.
    Authors: Lu and Sewer
    J Biol Chem  2015;35:1223

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