receptor antagonist, approximately 50-fold selective over σ2
sites and ≥100-fold selective over opioid, PCP, muscarinic, dopamine, α1
receptors. Prevents hyperlocomotion following cocaine administration in mice.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Novel σ receptor ligands attenuate the locomotor stimulatory effects of cocaine.
McCracken et al.
Cocaine up-regulated fra-2 and σ-1 receptor gene and protein expression in brain regions involved in addiction and reward.
Liu et al.
Characterisation of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism.
Matsumoto et al.
The citations listed below are publications that use Tocris products. Selected citations for BD 1063 dihydrochloride include:
Showing Results 1 - 9 of 9