BDNF (human)

Catalog # Availability Size / Price Qty
2837/10U
BDNF (human)
1 Image
Description: Activates TrkB and p75 receptors
Product Details
Citations (6)
Reviews

Biological Activity

Member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. Enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.

Technical Data

M.Wt:
26984
Solubility:
Soluble in water
Storage:
Store at -20°C
CAS No:
218441-99-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity.
    Lipsky and Marini
    Ann.N.Y.Acad.Sci., 2007;1122:130
  2. Neurotrophic factors as a therapeutic target for Parkinson's disease.
    Evans and Barker
    Expert Opin.Ther.Targets, 2008;12:437
  3. The when and where of BDNF and the antidepressant response.
    Wang et al.
    Biol.Psychiat., 2008;63:640

Product Datasheets

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