Catalog Number: 2837
Biological Activity
Member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. Enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
Technical Data
  • M.Wt:
  • Solubility:
    Soluble in water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity.
    Lipsky and Marini
    Ann.N.Y.Acad.Sci., 2007;1122:130
  2. Neurotrophic factors as a therapeutic target for Parkinson's disease.
    Evans and Barker
    Expert Opin.Ther.Targets, 2008;12:437
  3. The when and where of BDNF and the antidepressant response.
    Wang et al.
    Biol.Psychiat., 2008;63:640

The citations listed below are publications that use Tocris products. Selected citations for BDNF (human) include:

Showing Results 1 - 3 of 3

  1. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons.
    Authors: Zhong Et al.
    Mol Pain
  2. Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin.
    Authors: Parsons Et al.
    J Biol Chem
  3. Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin.
    Authors: Hossaini Et al.
    Cell Metab
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