Catalog Number: 2837
Biological Activity
Member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. Enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
Technical Data
  • M.Wt:
  • Solubility:
    Soluble in water
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity.
    Lipsky and Marini
    Ann.N.Y.Acad.Sci., 2007;1122:130
  2. Neurotrophic factors as a therapeutic target for Parkinson's disease.
    Evans and Barker
    Expert Opin.Ther.Targets, 2008;12:437
  3. The when and where of BDNF and the antidepressant response.
    Wang et al.
    Biol.Psychiat., 2008;63:640

The citations listed below are publications that use Tocris products. Selected citations for BDNF (human) include:

3 Citations: Showing 1 - 3
Filter your results:

  1. BDNF interacts with endocannabinoids to regulate cocaine-induced synaptic plasticity in mouse midbrain dopamine neurons.
    Authors: Zhong Et al.
    Mol Pain 2015;35:4469
  2. Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin.
    Authors: Parsons Et al.
    J Biol Chem 2014;289:3518
  3. Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin.
    Authors: Hossaini Et al.
    Cell Metab 2010;6:43

Have you used BDNF (human)?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information


Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 


Customer Information