Benazepril hydrochloride

Tocris Bioscience | Catalog # 2578

Angiotensin-converting enzyme (ACE) inhibitor
Tocris Bioscience
Discontinued Product
2578 has been discontinued. View all ACE Inhibitors products.

Key Product Details

Description

Angiotensin-converting enzyme (ACE) inhibitor

Alternative Names

CGS 14824A
View all ACE Inhibitors »

Product Description

Benazepril hydrochloride is a non-peptide angiotensin-converting enzyme (ACE) inhibitor. Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats.

Product Specifications for Benazepril hydrochloride

Molecular Weight

460.96

Formula

C24H28N2O5.HCl

Storage

Desiccate at +4°C

Purity

≥99% (HPLC)

Chemical Name

(3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride

CAS Number

86541-74-4

PubChem ID

5362123

InChI Key

VPSRQEHTHIMDQM-FKLPMGAJSA-N

SMILES

O=[C@@](OCC)[C@H](CCC3=CC=CC=C3)N[C@H]1CCC2=C(C=CC=C2)N(CC(O)=O)C1=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 23.05 50
DMSO 46.1 100

Preparing Stock Solutions for Benazepril hydrochloride

The following data is based on the product molecular weight 460.96.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.17 mL 10.85 mL 21.69 mL
5 mM 0.43 mL 2.17 mL 4.34 mL
10 mM 0.22 mL 1.08 mL 2.17 mL
50 mM 0.04 mL 0.22 mL 0.43 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 23 publications citing the usage of this product.

  • Ishibashi Hemodynamic effects of benazepril, an angiotensin-converting enzyme inhibitor, as studied in conscious normotensive dogs. Cardiovas.Drugs Ther.
  • Yamamoto General pharmacology of the novel angiotensin converting enzyme inhibitor benaz. hydrochloride. Effects on cardiovascular, visceral and renal functions and on hemodynamics. Arzneim.-Forsch.
  • Takemori Effect of benaz. hydrochloride on cardiac hypertrophy in spontaneous hypertensive rats. Arzneim.-Forsch.

Product Documents for Benazepril hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Benazepril hydrochloride

For research use only

Related Research Areas

Metalloproteases and Regulators

Citations for Benazepril hydrochloride

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