Bepridil hydrochloride
Tocris Bioscience | Catalog # 4117
Key Product Details
Description
Product Description
Bepridil hydrochloride is a calcium channel blocker. Also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels; opens mitochondrial KATP channels. Antiarrhythmic and antihypertensive; acts as a calcium sensitizer.
Product Specifications for Bepridil hydrochloride
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 40.3 | 100 |
Preparing Stock Solutions for Bepridil hydrochloride
The following data is based on the product molecular weight 403.00.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.48 mL | 12.41 mL | 24.81 mL |
| 5 mM | 0.50 mL | 2.48 mL | 4.96 mL |
| 10 mM | 0.25 mL | 1.24 mL | 2.48 mL |
| 50 mM | 0.05 mL | 0.25 mL | 0.50 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.
- Gill Pharmacology of bepridil. Am.J.Cardiol. 1992 PMID: 1372785
- Wantanabe and Kimura Blocking effect of bepridil on Na+/ Ca2+ exchange current in gunea pig cardiac ventricular myocytes. Jpn.J.Pharmacol. 2001 PMID: 11388640
- Sato Bepridil, an antiarrythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection. J.Pharmacol.Exp.Ther. 2006 PMID: 16174795
- Yatani Bepridil block of cardiac calcium and sodium channels. J.Pharmacol.Exp.Ther. 1986 PMID: 2420970
Product Documents for Bepridil hydrochloride
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Bepridil hydrochloride
For research use only
Related Research Areas
Citations for Bepridil hydrochloride
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Species: HumanVerified Customer | Posted 02/04/2019Product used on Cav1.2 channels to understand it blocking mechanism on the specific channel.
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