Bepridil hydrochloride
Chemical Name: N-Benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)aniline hydrochloride
Purity: ≥99%
Biological Activity
Calcium channel blocker. Also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels; opens mitochondrial KATP channels. Antiarrhythmic and antihypertensive; acts as a calcium sensitizer.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Pharmacology of bepridil.
Gill et al.
Am.J.Cardiol., 1992;69:11D -
Bepridil block of cardiac calcium and sodium channels.
Yatani et al.
J.Pharmacol.Exp.Ther., 1986;237:9 -
Blocking effect of bepridil on Na+/ Ca2+ exchange current in gunea pig cardiac ventricular myocytes.
Wantanabe and Kimura
Jpn.J.Pharmacol., 2001;85:370 -
Bepridil, an antiarrythmic drug, opens mitochondrial KATP channels, blocks sarcolemmal KATP channels, and confers cardioprotection.
Sato et al.
J.Pharmacol.Exp.Ther., 2006;316:182
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for Bepridil hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Bepridil hydrochloride include:
1 Citation: Showing 1 - 1
-
Intracellular and extracellular pH and Ca are bound to control mitosis in the early sea urchin embryo via ERK and MPF activities.
Authors: Ciapa and Philippe
PLoS One 2013;8:e66113
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for Bepridil hydrochloride
Average Rating: 5 (Based on 1 Review)
Have you used Bepridil hydrochloride?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Filter by:
Product used on Cav1.2 channels to understand it blocking mechanism on the specific channel.
