Catalog Number: 1956
Alternate Names: Ubenimex
Chemical Name: N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine
Biological Activity
Aminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.
Technical Data
  • M.Wt:
    308.38
  • Formula:
    C16H24N2O4
  • Solubility:
    Soluble to 50 mM in 1eq. NaOH
  • Purity:
    >99%
  • Storage:
    Desiccate at +4°C
  • CAS No:
    58970-76-6
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effect of ubenimex (Bestatin) on the cell growth and phenotype of HL-60 and HL-60R cell lines: up- and down-regulation of CD13/aminopeptidase N.
    Imamura and Kimura
    Leuk.Lymphoma, 2000;37:663
  2. Bestatin as an experimental tool in mammals.
    Scornik and Botbol
    Curr.Drug Metab., 2001;2:67
  3. Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes.
    Umezawa et al.
    J.Antibiot., 1976;29:97

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