Bestatin
Tocris Bioscience | Catalog # 1956
Key Product Details
Description
Alternative Names
Product Description
Bestatin is an aminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.
Product Specifications for Bestatin
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 3.08 | 10 |
Preparing Stock Solutions for Bestatin
The following data is based on the product molecular weight 308.38.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.43 mL | 162.14 mL | 324.28 mL |
| 0.5 mM | 6.49 mL | 32.43 mL | 64.86 mL |
| 1 mM | 3.24 mL | 16.21 mL | 32.43 mL |
| 5 mM | 0.65 mL | 3.24 mL | 6.49 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 19 publications citing the usage of this product.
- Scornik and Botbol Bestatin as an experimental tool in mammals. Curr.Drug Metab. 2001 PMID: 11465152
- Umezawa Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. J.Antibiot. 1976 PMID: 931798
- Imamura and Kimura Effect of ubenimex (Bestatin) on the cell growth and phenotype of HL-60 and HL-60R cell lines: up- and down-regulation of CD13/aminopeptidase N. Leuk.Lymphoma 2000 PMID: 11042531
Product Documents for Bestatin
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Bestatin
For research use only
Citations for Bestatin
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Species: MouseAssay Type: Ex VivoVerified Customer | Posted 05/14/2019Used for slice electrophysiology work; bath applied with the opioid peptide dynorphin A to prevent its degradation with great results.
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