Chemical Name: N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-leucine
Biological ActivityBestatin is an aminopeptidase inhibitor (Ki = 0.001 - 90 mM); inhibits enkephalin metabolism and leukotriene A4 hydrolase. Inhibits tumor cell proliferation.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Effect of ubenimex (Bestatin) on the cell growth and phenotype of HL-60 and HL-60R cell lines: up- and down-regulation of CD13/aminopeptidase N.
Imamura and Kimura
Bestatin as an experimental tool in mammals.
Scornik and Botbol
Curr.Drug Metab., 2001;2:67
Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes.
Umezawa et al.
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