BIBR 1532

Catalog # Availability Size / Price Qty
2981/10
2981/50
BIBR 1532 | CAS No. 321674-73-1 | Telomerase Inhibitors
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Description: Selective telomerase inhibitor

Chemical Name: 2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoic acid

Purity: ≥98%

Product Details
Citations (2)
Reviews (1)

Biological Activity

Selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCI-H460 lung carcinoma cells and eventual growth arrest.

Technical Data

M.Wt:
331.36
Formula:
C21H17NO3
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
321674-73-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for BIBR 1532

The citations listed below are publications that use Tocris products. Selected citations for BIBR 1532 include:

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Telomerase inhibitor in vitro
By Maria Garcia Gonzalez on 07/12/2018
Application: Species: Rat

Used BIBR 1532 as telomerase inhibitor at 2.5 uM with reproducible but moderate effects (expected).


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