BIBR 1532

  ( 2 citations )    
Product Datasheet
Catalog Number:2981
Chemical Name:2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoic acid
Product Details
Citations (2)
Reviews
Biological Activity
Selective telomerase inhibitor (IC50 values are 93, > 100000 and > 100000 nM for human telomerase, human RNA polymerase I and human RNA polymerase II + III respectively). Causes telomere shortening in exponentially growing NCI-H460 lung carcinoma cells and eventual growth arrest.
Technical Data
  • M.Wt:
    331.36
  • Formula:
    C21H17NO3
  • Solubility:
    Soluble to 100 mM in DMSO and to 25 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at RT
  • CAS No:
    321674-73-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for BIBR 1532 include:

2 Citations: Showing 1 - 2
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  1. Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.
    Authors: Beyer Et al.
    Circ Res  2016;118:856
  2. Telomerase efficiently elongates highly transcribing telomeres in human cancer cells.
    Authors: Farnung Et al.
    PLoS One  2012;7:e35714

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